Participants in the UK’s longest-running birth cohort study are turning 80 this year.
The MRC National Survey of Health and Development (NSHD46) was established after WWII initially to investigate the costs associated with pregnancy. The study subsequently looked at socioeconomic and environmental impacts on morbidity, educational attainment and earnings. As the cohort gets older, the focus has shifted to investigating the processes of ageing using in-depth brain and heart phenotyping, and the use of health and social care services.
NSHD46 provides researchers with a wealth of opportunities to investigate how early and mid-life experiences may have an impact on health and wellbeing in later life. More information about the characteristics of NSHD46 and how to apply to access its data via UK LLC is available on
Guidebook.